Mexico’s drug cartels generate over $12 billion annually—far surpassing Colombia’s cartels—according to the 2025 UN World Drug Report. Cocaine, heroin, and meth trafficking drive profits. Mexican drug cartels are now the world’s top-earning criminal organizations in the drug trade, generating a staggering $12.1 billion annually—far outpacing their Colombian counterparts. That’s one of the key takeaways from the 2025 World Drug Report released Thu…