‘Fasting-mimicking’ diet said to reduce risk factors for aging

Following a diet that mimics fasting may reduce risk factors for disease in generally healthy people, according to a small study.

Dr. Min Wei of UCLA’s Longevity Institute and colleagues tested the effects of the fasting-mimicking diet on various risk factors for diabetes, heart disease, cancer or other conditions.

The diet (FMD; brand name ProLon) is low in calories, sugars and protein but high in unsaturated fats. Forty-eight study participants ate normally for three months while 52 ate FMD for five days each month and ate normally the rest of the time. After three months, the groups switched regimens. Although all participants were considered healthy, some had high blood pressure, low levels of “good” cholesterol, and other risk factors.

A total of 71 people completed the study, which was published in Science Translational Medicine. Body mass index, blood pressure, blood sugar and cholesterol improved with FMD, but mainly for those who were already at risk. Side effects were mild, including fatigue, weakness and headaches.

Wei and Dr. Valter Longo of the University of California, San Diego, said in an interview published in the journal that while “the great majority” of participants had one or more risk factors for diseases such as diabetes, heart disease or cancer, “FDA trials will be necessary to demonstrate whether periodic FMD is effective in disease prevention and treatment.”

Dr. Joseph Antoun, CEO of L-Nutra, Inc., which produces FMD, told Reuters Health by email that FMD “is intended for use by individuals who want to optimize their health and wellbeing, by overweight or obese individuals who want to manage their weight in an easy and healthy way, and by people who have abnormal levels of biomarkers for aging and age-related conditions.”

That said, Antoun acknowledged that if you have common conditions associated with overweight and obesity such as diabetes, cardiovascular disease and cancer, you should not use FMD without a doctor’s approval.

The product also should not be used by children under 18 or pregnant or nursing women. And it’s not for you if you have certain metabolic diseases, liver or kidney disorders that may be affected by the very low glucose and protein content of the diet, or if you have nut or soy allergies. What’s more, it “should never be combined with glucose-lowering drugs, such as metformin or insulin,” according to Antoun.

Registered dietitian Ashlea Braun of the Ohio State University Wexner Medical Center in Columbus pointed out that researchers compared the fasting-mimicking diet to participants’ usual diet. “Therefore, we don’t yet know how this diet stands up against long-standing approaches already shown to be beneficial, such as the Mediterranean or DASH Diet.”

“It’s not clear if (FMD) enables individuals to consistently meet all micronutrient requirements,” she told Reuters Health by email. “It’s also not known how this type of restrictive diet affects muscle mass in the long term, and what impact this has on various indicators of health.”

“Although there is some evidence showing these type of restrictive diets can help ‘jump start’ people considering lifestyle changes, more research is definitely needed before this is recommended for individuals,” Braun concluded.

SOURCE: bit.ly/2keeNFn Science Translational Medicine, online February 15, 2017.

Following a diet that mimics fasting may reduce risk factors for disease in generally healthy people, according to a small study.

Dr. Min Wei of . . .

Follow Us On Google News | Get Our Newsletter



Trending News on PVDN

  • sargassum-slams-cancun-playa-restaurantsSargassum Crisis in Cancún and Playa del Carmen Forces Restaurants and Beach Clubs to Cut Staff Businesses in Cancún and Playa del Carmen report steep losses due to sargassum, with restaurants losing diners and beach clubs sending staff on unpaid leave. Restaurants and beach clubs along the shores of Puerto Juárez in Cancún and Playa del Carmen are grappling with a sharp downturn in business due to a relentless invasion of…
  • cancun-beaches-50-tons-sargassum-cleanupCancún beach overwhelmed by over 50 tons of sargassum in 24 hours Over 50 tons of sargassum were removed from Cancún’s Chac Mool Beach in just 24 hours, as authorities ramp up cleaning efforts across three key public beaches. Cancún’s white-sand beaches are under pressure once again as an unusually large volume of sargassum has washed ashore in the last 24 hours, disrupting tourism and triggering a…
  • cancun-hotels-sargassum-cleanup-failuresCancún government demands answers from hotels on sargassum cleanup failures Mayor Ana Paty Peralta will meet with hotel leaders in Cancún to address failures in sargassum cleanup efforts, amid growing environmental and public health concerns. The municipal government of Benito Juárez is taking a firmer stance on the growing sargassum problem in Cancún, calling on the hotel industry to explain its inadequate handling of seaweed…
  • sargassum-free-beaches-quintana-roo-summer-2025Sargassum-Free Beaches in Quintana Roo for Summer 2025, including beaches in Cancún Travelers looking for sargassum-free beaches in Quintana Roo this summer can still find clear waters in Isla Mujeres and parts of Cancún, according to updated reports. As the summer travel season ramps up, much of the Caribbean coast is once again dealing with sargassum, the brown seaweed that washes ashore in thick mats and affects…
  • puerto-vallarta-flooding-landslide-hurricane-erickHeavy rains flood Puerto Vallarta streets and trigger landslide in tunnel Flooding from remnants of Hurricane Erick paralyzed key roads in Puerto Vallarta and caused a landslide in the Luis Donaldo Colosio tunnel, Civil Protection continues damage assessment. The city of Puerto Vallarta was overwhelmed Thursday night by heavy rainfall that caused major flooding, stranded vehicles, and triggered a landslide in the Luis Donaldo Colosio bypass…
  • Body with signs of crocodile attack found in Ameca River, a leg was found last monthBeaches Closed in Nuevo Vallarta and Lo de Marcos After Crocodile Sighting Authorities temporarily close beaches in Nuevo Vallarta and Lo de Marcos after a crocodile was spotted in shallow waters. Tourists are urged to follow lifeguard guidance. Beaches in Nuevo Vallarta and Lo de Marcos were temporarily closed to the public on Friday, June 20, after a crocodile was spotted swimming close to shore, prompting swift…
  • bus-crashes-canal-puerto-vallartaBus crashes into canal in Puerto Vallarta’s 5 de Diciembre neighborhood A public transport bus crashed into a drainage canal in Puerto Vallarta’s 5 de Diciembre area. Authorities responded quickly, and no serious injuries were reported. A public transport bus veered off the road and plunged into a stormwater canal early Thursday morning in Puerto Vallarta’s 5 de Diciembre neighborhood, sparking concern among locals but leaving…
  • heavy-rain-flooding-landslides-puerto-vallartaTrash-Choked Drains Make Puerto Vallarta Flooding Worse During Heavy Rain Overflowing storm drains clogged with garbage are fueling flooding in Puerto Vallarta, officials warn, as rains bring chaos to multiple neighborhoods. As heavy rain swept across Puerto Vallarta Thursday night and into Friday morning, flooding was widespread—but officials say much of the chaos was avoidable. The city’s stormwater drains, overwhelmed not just by rainfall but…
  • Know your consumer rights in Mexico Is it legal for restaurants to include the tipPuerto Vallarta restaurants face 33 percent staff shortage Restaurants in Puerto Vallarta face a 33% staffing shortfall as they prepare for a busy summer holiday season, aiming to boost sales by up to 60% despite ongoing labor challenges. As Puerto Vallarta prepares to welcome a surge of summer tourists, the city’s restaurant sector is grappling with a serious staffing problem—operating with roughly one-third…
  • tropical-storm-erick-warnings-mexico-coastHurricane Erick will bring heavy rains to Puerto Vallarta Hurricane Erick Puerto Vallarta will bring heavy rains to Puerto Vallarta by Friday but poses no risk to the northern coast of Jalisco. Meteorologist Víctor Manuel Cornejo López, of the Civil Protection scientific committee for the Bay, reports that Hurricane Erick will deliver significant rainfall to Puerto Vallarta without threatening the region’s safety. According to…
Scroll to Top